Real-world data is data that is generated through routine health operations, often in the electronic health record or administrative claims. We have established collaborations with several sources of real-world data with granular treatment and cancer-specific data. We aim to use this broad data to study many important areas, including the clinical and policy impacts of the COVID-19 pandemic, patterns of novel drug utilization and effectiveness, and to develop methodologies for in-silico trials that shed light into drug effectiveness.